Preventing haemolysis
Why samples haemolyse, which results it affects, and what you can do about it.
What haemolysis is
Haemolysis is the rupture of red blood cells, which releases their contents into the serum or plasma. It is a common reason laboratories reject samples, and it can falsely raise results such as potassium.
Common causes
A needle too fine for the draw, forcing blood through a syringe, excessive vacuum, shaking tubes, a tourniquet left on too long, drawing through a haematoma, and rough handling or temperature extremes in transport.
Reducing it
Use the largest suitable gauge, let blood flow at its natural rate, fill tubes to the line, invert gently, release the tourniquet promptly, and transport samples carefully.
Using feedback
If your laboratory reports rejected samples, use that feedback to review your own technique.
General information only. It is not accredited CPD and does not replace your training, your employer's procedures or the receiving laboratory's requirements.
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